General Information

  • ID:  hor002581
  • Uniprot ID:  A8XJA5
  • Protein name:  NLP
  • Gene name:  pdf-2
  • Organism:  Caenorhabditis briggsae
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway; GO:0007567 parturition; GO:0035641 locomotory exploration behavior; GO:0040011 locomotion; GO:0045475 locomotor rhythm
  • GO CC:  NA

Sequence Information

  • Sequence:  NNAEVVNHLLKNFGTLDRLGDV
  • Length:  22
  • Propeptide:  MSSRISVTLLLLVAVAIMLVGVNVVEANPRPQGNMLRYGNSLPAYAPHVLYRFYNSRQFAPQMKRNNAEVVNHLLKNFGTLDRLGDVGK
  • Signal peptide:  MSSRISVTLLLLVAVAIMLVGVNVVEA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A8XJA5-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002581_AF2.pdbhor002581_ESM.pdb

Physical Information

Mass: 281350 Formula: C106H172N32O34
Absent amino acids: CIMPQSWY Common amino acids: LN
pI: 5.52 Basic residues: 3
Polar residues: 7 Hydrophobic residues: 9
Hydrophobicity: -23.64 Boman Index: -4004
Half-Life: 1.4 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 115
Instability Index: -843.18 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  18760316
  • Title:  Comparative Peptidomics of Caenorhabditis Elegans Versus C. Briggsae by LC-MALDI-TOF MS